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Table 2 Description of reactions

From: The use of direct oral challenge to confirm allergies to penicillin class antibiotics in Danish children

  Total Negative Positive
Reaction to AB before referral to DC 140 136 4
 Once 128 (91%) 124 (91%) 4 (100%)
 More than once 12 (8.6%) 12 (8.8%)  
Time period from AB dose to symptoms 135 131 4
  < 1 day 86 (64%) 84 (64%) 2 (50%)
 1–2 days 27 (20%) 25 (19%) 2 (50%)
  > 2 days 22 (16%) 22 (17%)  
Duration of symptoms 137 133 4
  < 1 day 66 (48%) 63 (47%) 3 (75%)
  > 1 day 60 (44%) 59 (44%) 1 (25%)
 Unknown 11 (8.0%) 11 (8.3%)  
Medical treatment 136 132 4
 None 105 (77%) 103 (78%) 2 (50%)
 Antihistamines 30 (22%) 28 (21%) 2 (50%)
 Corticosteroids 8 (5.8%) 8 (6.1%)  
 Epinephrine 1 (0.7%) 1 (0.8%)  
 Bronchodilators 2 (1.5%) 2 (1.5%)  
Indication of AB treatment 133 129 4
 Airway infection 17 (13%) 16 (12%) 1 (25%)
 Tonsillitis 21 (16%) 21 (16%)  
 Sinusitis/otitis 76 (57%) 73 (57%) 3 (75%)
 Other (impetigo, arthritis etc.) 15 (11%) 15 (12%)  
 Unknown 4 (3.0%) 4 (3.1%)  
  1. Total: all children; Negative: children with a negative provocation test; Positive: children with a positive provocation test